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・ Argimiro España
・ Argimusco
・ Argin
・ Argina
・ Argina amanda
・ Argina astrea
・ Argina, Armenia
・ Arginae
・ Arginase
・ Arginbaatar
・ Arginia
・ Arginine
・ Arginine (data page)
・ Arginine 2-monooxygenase
・ Arginine alphaketoglutarate
Arginine and proline metabolism
・ Arginine carboxypeptidase
・ Arginine catabolic mobile element
・ Arginine decarboxylase
・ Arginine deiminase
・ Arginine glutamate
・ Arginine kinase
・ Arginine N-succinyltransferase
・ Arginine racemase
・ Arginine repressor ArgR
・ Arginine vasopressin receptor 1A
・ Arginine vasopressin receptor 1B
・ Arginine vasopressin receptor 2
・ Argininemia
・ Arginine—pyruvate transaminase


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Arginine and proline metabolism : ウィキペディア英語版
Arginine and proline metabolism
Arginine and proline metabolism is one of the central pathways for the biosynthesis of the amino acids arginine and proline from glutamate. The pathways linking arginine, glutamate, and proline are bidirectional. Thus, the net utilization or production of these amino acids is highly dependent on cell type and developmental stage.
==Reactions==
Proline is biosynthetically derived from the amino acid L-glutamate. Glutamate-5-semialdehyde is first formed by glutamate 5-kinase (ATP-dependent) and glutamate-5-semialdehyde dehydrogenase (which requires NADH or NADPH). This can then either spontaneously cyclize to form 1-pyrroline-5-carboxylic acid, which is reduced to proline by pyrroline-5-carboxylate reductase (using NADH or NADPH), or turned into ornithine by ornithine aminotransferase, followed by cyclisation by ornithine cyclodeaminase to form proline.〔.〕
Citrulline is made from ornithine and carbamoyl phosphate by ornithine carbamoyltransferase. Arginine is then synthesized from citrulline in the urea cycle by the sequential action of the cytosolic enzymes argininosuccinate synthetase (ASS) and argininosuccinate lyase (ASL).

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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